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Our top choices for Southwest Coast Florida hotels

A modern hotel lobby with a reception desk, seating area, and a dining section.

1. Holiday Inn Express & Suites Fort Myers Airport by IHG

Daniels Corridor

Brian

CA $170 total

includes taxes & fees

Nov 13 - Nov 14

A hotel with a modern design, featuring a prominent 'Best Western' sign, multiple parking spaces, and palm trees.

2. Best Western Fort Myers Inn & Suites

Fort Myers

Azael

CA $126 total

includes taxes & fees

Nov 11 - Nov 12

A hotel room with a large bed, a wooden headboard, a nightstand, and a chair.

3. Days Inn & Suites by Wyndham Fort Myers Near JetBlue Park

Daniels Corridor

Merlin

CA $104 total

includes taxes & fees

Nov 10 - Nov 11

A gym with exercise equipment, a wall-mounted TV, and a towel rack.

4. Hampton Inn Fort Myers-Airport & I-75

Daniels Corridor

Bruce

CA $134 total

includes taxes & fees

Nov 22 - Nov 23

A hotel room with a bed, a desk, a chair, and a small table.

5. SpringHill Suites by Marriott Fort Myers Airport

Daniels Corridor

Jon B.

CA $139 total

includes taxes & fees

Nov 29 - Nov 30

A modern kitchen area with a breakfast bar, fruit display, and a chalkboard menu.

6. Hampton Inn Fort Myers Downtown

Fort Myers River District

Donald

CA $167 total

includes taxes & fees

Nov 25 - Nov 26

7. Hyatt Place Fort Myers/at The Forum

The Forum

Cornel

CA $150 total

includes taxes & fees

Nov 15 - Nov 16

A Drury Inn & Suites hotel with a parking lot full of cars.

8. Drury Inn & Suites Fort Myers Airport FGCU

Miromar Lakes

Giselia Dos Santos

CA $187 total

includes taxes & fees

Dec 1 - Dec 2

A Comfort Inn & Suites hotel with a covered entrance, palm trees, and a well-lit facade.

9. Comfort Inn & Suites Fort Myers Airport

Daniels Corridor

Frank

CA $112 total

includes taxes & fees

Nov 30 - Dec 1

A reception area with a modern design, featuring a wooden panel wall with integrated lighting, a reception desk, and a refrigerator stocked with beverages.

10. Comfort Suites Fort Myers East I-75

Fort Myers

Eloan

CA $148 total

includes taxes & fees

Nov 22 - Nov 23

A hotel room with two beds, a wooden headboard, a nightstand with a lamp, and a window with curtains.

11. Holiday Inn Express Cape Coral-Fort Myers Area by IHG

Caloosahatchee

Sherri

CA $159 total

includes taxes & fees

Nov 15 - Nov 16

A modern lobby with a reception desk, two colorful armchairs, a large window, and a decorative ceiling light fixture.

12. Quality Suites Fort Myers I-75

Daniels Corridor

Joanne

CA $106 total

includes taxes & fees

Nov 11 - Nov 12

A swimming pool with a stone wall and palm trees, surrounded by a building with large windows and outdoor seating.

13. Doubletree by Hilton Fort Myers at Bell Tower Shops

Villas

James

CA $173 total

includes taxes & fees

Nov 22 - Nov 23

A hotel room with a large bed, a wooden headboard, two bedside lamps, a chair, and a painting on the wall.

14. Extended Stay America Premier Suites - Fort Myers - Airport

Daniels Corridor

Isaura

CA $108 total

includes taxes & fees

Dec 6 - Dec 7

A modern kitchen with a breakfast bar, various food items, and a chalkboard menu.

15. Hampton Inn & Suites Fort Myers - Colonial Blvd

Fort Myers

Luis

CA $159 total

includes taxes & fees

Nov 22 - Nov 23

16. HomeTowne Studios by Red Roof Fort Myers

Fort Myers

Ashley

CA $102 total

includes taxes & fees

Nov 12 - Nov 13

A row of turquoise Adirondack chairs with umbrellas, a wooden deck, and a marina in the background.

17. Latitude 26 Waterfront Boutique Resort - Fort Myers Beach

Siesta Isle

Giovanna

CA $149 total

includes taxes & fees

Nov 10 - Nov 11

A hotel with a covered entrance, palm trees, and a well-maintained garden.

18. Homewood Suites by Hilton - Fort Myers

Villas

Anne

CA $173 total

includes taxes & fees

Nov 15 - Nov 16

An outdoor patio area with a stone fire pit, seating, and string lights.

19. SpringHill Suites by Marriott Fort Myers Estero

Estero

Nail

CA $197 total

includes taxes & fees

Nov 13 - Nov 14

20. Quality Inn & Suites Lehigh Acres Fort Myers

Lehigh Acres

Exia

CA $94 total

includes taxes & fees

Nov 15 - Nov 16

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Vacation Rentals in Southwest Coast Florida

Aparthotel

A balcony with a TV, a chair, and a view of a beach with a pier.

Edison Beach House

Fort Myers Beach

"Best place ever"

Aparthotel

A beach with a thatched-roof structure, palm trees, and a view of the sea.

The Suites at Fishermen’s Village

Punta Gorda Isles

"Great place to stay but comes with a price."

Apartment

A swimming pool with lounge chairs and a building with a sloped roof in the background.

Landing Apartments Fort Myers near Eastwood Village

Fort Myers

"Amazing , safe and beautiful place to stay . I was there for over 3 weeks and it’s local to many great locations , quiet and safe and over all highly recommend."

Aparthotel

A modern hotel room with a kitchenette, a bed, a seating area, and a wardrobe.

StudioRes by Marriott Fort Myers Airport

Fort Myers

"Location was great."

Aparthotel

A modern kitchen with a large island, a dining area with chairs, and a view of the outdoors.

Sanibel Siesta on the Beach

Mid Island

"Great location and close to beach. Rooms nice and it had everything you needed for the beach. Pool wonderful"

Aparthotel

A modern kitchen with a central island, black bar-style chairs, pendant lighting, and a large window with curtains.

Landing Apartments Fort Myers near Olympia Pointe

Fort Myers

"Great pool,comfortable room."

Apartment

A modern building with a white exterior, a brick gable, and a palm tree in the foreground.

Pelican Post at Anna Maria Island Inn

Bradenton Beach

"Location was perfect"

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Stay near popular Southwest Coast Florida attractions

A lifeguard tower with an American flag, a green flag, and a signboard on a beach with people sunbathing and umbrellas.

Siesta Key Beach

9.6/10 (4,113 reviews)

The soft, white sand on Siesta Key’s award-winning family-friendly beach is perfect for relaxing under a sun umbrella and taking part in a game of volleyball.

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Learn more about Southwest Coast Florida

Amazing beaches, island views, and top sights from Key West Express to Siesta Key Beach—discover Southwest Coast Florida, a destination also famous for its live music scene.

See all hotels in Southwest Coast Florida

A sunset over a beach with a pier and people walking on the sand.

Top Southwest Coast Florida Hotel Reviews

Great Wolf Lodge Naples

10/10 Excellent

"La estancia fue espectacular el mejor hotel para niños le doy un 1000 de diez en todo excepto la limpieza del cuarto qué fue un 1 de dies las colchas de las literas de los niños nunca se cambian al igual que las del sofá cama olían muy mal el sábado entro una muchacha a limpiar encontré una identificación de su nombre que decía mendoza la cual no estaba el viernes cuando llegamos porque desarmé todo el sofá cama y no había nada cuya identificación me pinché pues era con un alfiler todo estaba menos un dulce de delfín 🐬 qué compramos en una tienda de dulces del hotel eso me desilusionó un poco el personal amable en todo momento lo único a mejorar debería ser la limpieza de los cuartos ponerles mas atención a las hausekeeper hasta las toallas estaban llenas de labial el cuarto sucio yo creo no es un hotel barato para encontrar un cuarto en esas condiciones el cuarto debería de repararse también pues esta falta de pintura en algunos lados y el papel del cuarto de la pared de las literas etaba despegado un pedazo por lo demás todo excelente solo los exorto poner un poco mas la atención a la limpieza de los cuartos y mantenimiento es lo único que estaba sucio y deja mucho que desear una habitación sucias y sobre todo con peste las colchas que uno se tapa hojala hicieran una reunión con la limpieza del cuarto y se lo plantearan por lo demás el personal tiene el hotel impecable limpiando a cada minuto una grandes felicidades a esa parte de h"

Spark by Hilton Sarasota Siesta Key Gateway

10/10 Excellent

"Staff was great. At the desk Ginny—at the bar Lynn and sorry to say I didn’t get the name of young lady who came to fix our TV Friday night very quickly took care of it for us. Recommendations made from staff on where to eat were excellent. We were there for a sad occasion (mom’s funeral mass)but it was great to have our family together in one place."